"Brave, funny, emotional, and one of the best films of the year."
— Nathaniel Muir, AIPT
"Mel Eslyn has created a funny and complicated film sure to provoke thought and discussion."
— Drew Gregory, Autostraddle
"Biosphere is an uproariously funny and clever buddy comedy that uses humor to talk about pressing societal issues."
— Daniel Feingold, Scripps News
"Hilarious and earnest, Mel Eslyn's directorial debut stars Sterling K. Brown and Mark Duplass as the last two men on Earth."
— Emma Stefansky, Indiewire
"Post-apocalyptic survival meets the anxious buddy humor of Humpday in Biosphere, a mysterious and hilarious pic that really can’t be discussed much without saying things a prospective viewer would be better off not hearing."
— John DeFore, Hollywood Reporter
"'Life finds a way'. You may remember this quote uttered from the mouth of one Jeff Goldblum in Steven Spielberg's action epic Jurassic Park but no other movie quite exemplifies the meaning of that quote more than Biosphere. Whether you want to laugh or you want to see a sincere story about gender, sexuality, a little bit of magic, and male friendship, Biosphere will help you find a way."
— Sean Doyle, Film Speak